Even the best skincare routine can hit a snag sometimes. Sure, serums and creams are great for everyday care, but they can't really tackle deeper issues like pitted acne scars, big pores, or skin that feels a bit loose. To actually change the texture of your skin for the better, you need to kickstart a healing response from within.
PRP microneedling works by taking a small sample of your blood to get the nutrient-rich plasma and putting it right into your skin. This triggers a huge boost in your body’s natural collagen and elastin production. It skips all the synthetic stuff and uses your own growth factors to help heal and rebuild your skin. It’s a super effective and all-natural way to smooth things out and create a firmer base for your skin.
The ultimate biological upgrade
PRP microneedling is a minimally invasive regenerative treatment that pairs controlled mechanical skin puncturing with the topical application of your body's own Platelet-Rich Plasma (PRP) to accelerate tissue repair and stimulate deep collagen and elastin production.
This autologous treatment uses your own biology to heal and rebuild, making it one of the most biocompatible procedures available in modern aesthetics.
| At A Glance | Treatment Facts |
| Best For | Skin texture, acne scars, enlarged pores, hair restoration |
| Treatment Type | Mechanical / Regenerative |
| Pain Level | 2/10 (Topical anesthetic applied) |
| Downtime | 24–48 hours (Social downtime) |
| Duration | 60–75 minutes |
| Results Appear | Initial glow in days; structural changes in 3–4 weeks |
| Longevity | 12+ months |
| Sessions | 3–6 recommended |
Versatility across the anatomy
Because this procedure triggers the body's natural healing cascade, it is highly versatile and effective across multiple treatment areas.
Engineering new collagen
The science relies on a two-step mechanism that forces the skin to repair itself at an accelerated rate.
First, the microneedling portion utilizes a medical-grade pen equipped with sterile, fine needles to create thousands of microscopic channels in the top layer of the skin. These micro-injuries signal the brain to send blood and collagen to the area.
Second, we apply your PRP (Platelet-Rich Plasma). Before the microneedling begins, we draw a small vial of your blood and spin it in a centrifuge to separate the red blood cells from the plasma. This isolates the platelets, which hold a massive reserve of growth factors. When we drive this liquid gold into the freshly created micro-channels, the plasma acts as a biological messenger, drastically amplifying collagen and elastin production and speeding up the healing process.
Cellular-level improvements
By utilizing your own biological material, the procedure offers profound structural improvements with a significantly lower risk of reaction compared to synthetic serums.
Safety and compatibility
Good candidates
Most Calabasas patients looking for proactive skin rejuvenation are excellent candidates. Because the treatment relies entirely on your own blood, it is generally considered safe for all Fitzpatrick skin types (from very fair to very deep), carrying zero risk of heat-induced hyperpigmentation, often associated with laser treatments.
Who is not a good fit?
We will turn away patients currently experiencing active acne breakouts, cystic lesions, or active eczema/rosacea flares in the treatment area, as gliding needles over active bacteria can spread infection. Individuals with compromised immune systems, blood-clotting disorders, or those currently taking heavy blood thinners are also contraindicated for this procedure.
Setting the stage for repair
Proper preparation ensures the highest quality plasma and minimizes the risk of bruising.
The clinical experience
We prioritize your comfort and the sterility of the environment throughout the entire treatment, which typically lasts about an hour.
The social timeline
Immediate downtime
You will experience minimal downtime in a physical sense, but you will look and feel like you have a moderate-to-severe sunburn. Your skin will be tight, red, and potentially slightly swollen. We leave the PRP serum on your face; do not wash it off until the following morning.
Social downtime
Plan for 24 to 48 hours of social downtime. By day two, the intense redness shifts to a light pink. By day three or four, you may experience mild flaking as the old skin turns over. You are fully restaurant-ready with makeup by day three.
Restrictions
Do not touch your face. Avoid sweating, heavy workouts, saunas, and direct sun exposure for at least 72 hours. Your skin channels are open, and introducing sweat or bacteria can cause adverse reactions. Do not apply makeup or sunscreen until 24 hours post-treatment.
Provider aftercare tips
Keep your routine incredibly simple for the first five days. Use a gentle, non-foaming cleanser and a basic hyaluronic acid moisturizer. Let the dead skin flake off naturally—do not scrub or pick at your face.
Watching the biology shift
Cellular regeneration requires patience, but the aesthetic payoff arrives in phases.
Maintaining the structure
The new collagen your body produces is permanent. However, your natural aging process continues. Once you complete your initial series of treatments, the structural improvements can last 12 to 18 months. We recommend booking a single maintenance session every 6 to 12 months to keep your collagen banks full and your skin functioning optimally.
Building the foundation
A single session provides a beautiful reset, but real structural change requires compounding effort. For general skin rejuvenation, we recommend a series of three to six treatments spaced 4 to 6 weeks apart. If we are treating deep acne scars or utilizing the protocol for hair restoration, six sessions are typically required to achieve optimal results.
Pricing your protocol
The cost of your microneedling procedure reflects the medical supplies required for the blood draw, the centrifuge processing, and the size of the treatment area. A session focused solely on the face will differ in price from a comprehensive face, neck, and chest treatment. During your consultation, we will map out a treatment plan, determine the exact number of sessions you need, and provide transparent package pricing.
Understanding the hierarchy
Basic Microneedling vs. PRP Microneedling
Standard microneedling relies solely on mechanical injury to stimulate collagen. Adding PRP amplifies the healing response exponentially. Patients who upgrade to PRP heal faster, experience less redness, and achieve significantly firmer skin than those who do basic microneedling alone.
PRP Microneedling vs. Laser Resurfacing
Lasers use heat to vaporize the top layers of skin. While highly effective, they require longer downtime and carry risks for darker skin tones. PRP microneedling is mechanically driven, meaning it generates no heat, making it universally safe for all skin types and seasons.
Stacking for efficiency
Absolutely. Because PRP microneedling focuses on surface texture and dermal thickness, it pairs perfectly with treatments that address underlying volume or muscle movement. We frequently schedule this treatment alongside Botox or Dermal Fillers (injected first, followed by microneedling). For patients focused on total systemic wellness, receiving IV Hydration Therapy during your numbing time is an excellent way to supercharge your cellular repair.
The clinical advantage
Isolating and applying human tissue requires strict medical oversight. At EllEve Med Spa, we do not treat blood-based procedures casually. Under the guidance of Irina Manukyan and our expert team, we adhere to hospital-grade sterility protocols for every blood draw and centrifugation process. We utilize advanced microneedling devices that create precise, vertical channels—preventing the dragging or tearing of the skin associated with older roller devices. We ensure your plasma is handled safely and applied effectively, maximizing your investment in your own biology.
It feels exactly like a routine blood test at your doctor's office. We only need a small amount of blood (typically one to two vials), and the process is over in less than a minute.
No. We strongly advise leaving the PRP serum on your skin overnight. This allows the maximum amount of growth factors to absorb into the micro-channels. You can gently wash your face with cool water the following morning.
Despite the dramatic name and viral photos, the procedure is not a bloody mess. We isolate the golden-colored plasma, leaving the red blood cells behind. While there may be pinpoint bleeding from the needles, your face will look slightly pink and glossy, not covered in blood.
PRP is highly effective for the under-eye area. We can microneedle the plasma directly over the orbital bone, which helps thicken the thin skin under the eyes, reducing the appearance of dark, hollow circles caused by thinning tissue.
You will likely experience mild flaking rather than sheet peeling. Around days three and four, the dead skin cells will gently slough off as the new, healthy skin emerges from underneath.
Your best resultsBegin Here
Your friendly and experienced aesthetic specialist at EllEve is here to help you find the most advanced and precise solutions, so you can live with optimal confidence. Contact us today to book your consultation and learn more about the services we offer.
Tue - Fri: 10AM – 6PM
Sat: 10AM – 4PM
